Biocell Guide

What is Collagen made of?

What is Collagen made of?

Answer: BioCell Collagen is a hydrolyzed chicken sternal cartilage derived dietary ingredient composed of a naturally-occurring matrix of hydrolyzed collagen type-II (≥300 mg), chondroitin sulfate (≥100 mg), hyaluronic acid (≥50 mg). BioCell Collagen is made from hormone- and antibiotic-free dietary chicken sternal cartilage. The composition of chicken sternal cartilage closely resembles that of human cartilage which improves bioavailability versus other Collagen Supplements.

What is Chicken Sternal Cartilage?

Answer : Cartilage is a clean and desirable source because it is free of impurities carried by blood vessels, lymphatics, and nerves. As a result, extracting solely from cartilage eliminates the risk of contamination. To ensure consistent quality and safety, we use a patented manufacturing procedure that subjects the chicken sternal cartilage to various processes such as filtration, purification, concentration, hydrolysis, and sterilization.

What is Chondroitin Sulfate?

Answer : Chondroitin sulfate is a chemical found in the cartilage of humans and animals and is an essential component of cartilage. Chondroitin sulfate is a naturally occurring compound that is an essential component of the cartilage that cushions the joints of the body.  In addition, it can be found in certain animal-based foods, such as bone broths, stews, soups, and other dishes containing connective tissue-rich meat cuts. According to proponents of Chondroitin sulfate the supplement increases the synthesis of various cartilage components and prevents cartilage breakdown.  (4).

What is Hyaluronic Acid?

Answer : Hyaluronic acid is a naturally occurring substance found in the eye and joint fluids. It provides cushioning and lubrication to the joints and other tissues. Hyaluronic Acid has the primary effect of retaining water to keep tissues and joints lubricated and moist. Hyaluronic acid occurs naturally in the skin, where it helps retain moisture by binding to water (1). By providing the body with additional hyaluronic acid to incorporate into the skin, hyaluronic acid supplements may prevent the loss of moisture and improve skin hyrdation (4, 5).

A 2014 study found that daily doses of 120–240 milligrams (mg) for at least one month significantly increased skin moisture and reduced dry skin in adults (3). Also, hydrated skin reduces the appearance of wrinkles, which may explain why hydration supplements can make skin appear smoother, according to multiple studies (6, 7). Hyaluronic acid serums applied to the skin’s surface can reduce wrinkles, redness, and dermatitis (8, 9, 10).

Why is Biocell Collagen different from other Collagen ingredients and products?

Biocell Collagen HA Matrix Technology

BioCell Collagen® goes beyond other collagen ingredients as it is a biomolecule matrix that contains hydrolyzed collagen type II peptides, chondroitin sulfate, and hyaluronic acid which improves absorption of Collagen in the human body. This results in improved hair, skin, nails, teeth and assists in reversing the visible signs of aging.

Scientifically researched ingredient

Seven human clinical trials show BioCell Collagen’s safety, efficacy, and bioavailability. Many collagen supplements lack human clinical studies and contain ineffective active ingredients. However Biocell Collagen has been scientifically reviewed in many clinical studies [1]. The ingredient has been extensively researched and has been shown to benefit skin, hair, teeth, nails and joints. Multiple human clinical studies showed that Biocell Collagen® promotes healthier joints and younger-looking skin as well as reversing visible signs of aging and improving the overall health of hair, skin, nails, teeth, gums and joints.

Purer form of deriving Collagen

The other difference between normal collagen ingredients and Biocell Collagen is that the majority of collagen ingredients on the market are derived from animal carcasses (e.g., cow, pig, and marine) and Biocell Collagen is derived from hydrolyzed chicken sternal cartilage which provides a much more pure form of Collagen that is more effective then collagen derived from animal carcasses.

Is Biocell Collagen safe?

BioCell Collagen is GRAS (Generally Recognized As Safe), non-GMO, and gluten, soy, shellfish, fish, egg, milk, peanuts, and sugar free. BioCell Collagen is only produced in the United States and Germany.

Work Cited :

Schwartz, S R. “Novel Hydrolyzed Chicken Sternal Cartilage Extract Improves Facial Epidermis and Connective Tissue in Healthy Adult Females: A Randomized, Double-Blind, Placebo-Controlled Trial.” https://pubmed.ncbi.nlm.nih.gov/31221944/

Jerosch, J. “Effects of Glucosamine and Chondroitin Sulfate on Cartilage Metabolism in OA: Outlook on Other Nutrient Partners Especially Omega-3 Fatty Acids”. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150191/

Walker, K. “Hyaluronic Acid.” https://www.ncbi.nlm.nih.gov/books/NBK482440/

Kimura, M. “Absorption of Orally Administered Hyaluronan.” https://pubmed.ncbi.nlm.nih.gov/27982756/

Gollner I. “Ingestion of an Oral Hyaluronan Solution Improves Skin Hydration, Wrinkle Reduction, Elasticity and Skin Roughness : Results of a Clinical Study.” https://pubmed.ncbi.nlm.nih.gov/27982756/

Kawada, C. “Ingested hyaluronan moisturizes dry skin.” https://pubmed.ncbi.nlm.nih.gov/25014997/

Michelotti, A. “Oral intake of a new full-spectrum hyaluronan improves skin profilometry and ageing: a randomized, double-blind, placebo-controlled clinical trial.” https://pubmed.ncbi.nlm.nih.gov/34933842/

Oe, M. “Oral hyaluronan relieves wrinkles: a double-blinded, placebo-controlled study over a 12-week period”. https://pubmed.ncbi.nlm.nih.gov/28761365/

Draelo, Z D. “Efficacy Evaluation of a Topical Hyaluronic Acid Serum in Facial Photoaging”. https://pubmed.ncbi.nlm.nih.gov/34176098/

Bukhari, S N. “Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects”. https://pubmed.ncbi.nlm.nih.gov/30287361/

Lee, Y. “Proteoglycan Combined with Hyaluronic Acid and Hydrolyzed Collagen Restores the Skin Barrier in Mild Atopic Dermatitis and Dry, Eczema-Prone Skin: A Pilot Study”. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508667/


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