Biocell Guide | Biocell Liquid Collagen
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Biocell Collagen FAQ
FAQs about BioCell Collagen
What is Biocell Collagen?
BioCell Collagen is a dietary supplement that was created to restore Collagen levels within the body to treat wrinkled skin, aging skin, exercise induced joint pain, osteoarthritis and sagging skin. It is composed of hydrolyzed type II collagen, chondroitin sulfate and hyaluronic acid.
BioCell Collagen might increase levels of collagen in the skin. Collagen gives skin its strength and elasticity. Clinical research demonstrates that BioCell Collagen supports active joints, youthful skin, and healthy connective tissues. BioCell Collagen effectiveness has been scientifically proven in numerous research studies including seven human clinical trials.
BioCell Collagen is clinically shown to:
Reduce facial fine lines, wrinkles and crow’s feet*
Reduce facial skin dryness/scaling*
Increase skin elasticity*
Increase skin collagen and hyaluronic acid content*
Promote joint comfort & mobility*
Enhance post-exercise recovery*
Support skin & joint collagens (type I, II & III)*
Help stimulate cartilage renewal*
Promote tendon and ligament connective tissue recovery following intense exercise*
Biocell Collagen FAQ
BioCell Collagen is derived from hormone- and antibiotic-free dietary chicken sternal cartilage.
The composition of chicken sternal cartilage is quite similar to that of human cartilage, which is rich in type II collagen, chondroitin sulfate, and hyaluronic acid.
Cartilage is a clean and ideal raw material since it is devoid of blood vessels, lymphatics, and nerves, all of which are known to transmit disease and contaminants.
As a result, extracting only from cartilage reduces the danger of contamination.
To assure consistent quality and safety, we employ a unique manufacturing approach that submits chicken sternal cartilage to a series of operations, including filtration, purification, concentration, hydrolysis, and sterilizing.
Additionally, it is critical to highlight that the synergy of biomolecules contained in BioCell’s proprietary matrix contributes significantly to its efficacy.
Numerous studies, including seven human clinical trials, demonstrate BioCell Collagen effectiveness, and bioavailability.
The bulk of collagen compounds available on the market are obtained from animal carcasses (e.g., cow, pig, and marine).
These materials are often composed of greater than 90% protein and are referred to as Collagen Peptides, Hydrolyzed Collagen, Collagen Hydrolysate, Collagen Type I & III, or Gelatin (also a form of hydrolyzed collagen).
BioCell Collagen is a branded dietary component that is a hydrolyzed chicken sternal cartilage extract made of a naturally occurring matrix of collagen type II peptides, chondroitin sulfate, and hyaluronic acid.
BioCell Collagen is self-certified GRAS (Generally Recognized As Safe), gluten-free, soy-free, shellfish-free, fish-free, egg-free, milk-free, peanut-free, and sugar-free.
BioCell Collagen is manufactured entirely in the United States of America and Germany.
BioCell Collagen is a nutritional supplement made entirely of hydrolyzed chicken sternal cartilage.
BioCell Collagen is made of 60% Hydrolyzed Collagen Type II (measured as Total Protein), 20% Chondroitin Sulfate, and 10% Hyaluronic Acid, according to independent laboratory examination.
Collagen is the most prevalent protein in cartilage and the skin’s dermis.
It supplies the structural underpinning for your connective tissues, which helps maintain the firmness and resilience of your skin and the activity and fluidity of your joints.
Chondroitin sulfate is a naturally occurring component of joint cartilage. It is responsible for the cartilage’s remarkable shock-absorbing qualities.
Hyaluronic acid (HA) is a chemical that aids in skin hydration, joint lubrication, and is the gel-like fluid that binds your cells together.
Additionally, it is critical to highlight that the synergy of biomolecules contained in BioCell’s proprietary matrix contributes significantly to its efficacy.
Numerous studies, including seven human clinical trials, demonstrate BioCell Collagen effectiveness, and bioavailability.
BioCell Collagen is gluten-free, soy-free, shellfish-free, fish-free, egg-free, milk-free, peanut-free, and sugar-free.
BioCell Collagen is not your typical collagen component.
BioCell Collagen is a clinically tested dietary component made of naturally occurring hydrolyzed type II collagen peptides, chondroitin sulfate, and hyaluronic acid.
BioCell’s proprietary matrix is not a concoction of separate chemicals.
The synergy of biomolecules contained in BioCell’s proprietary matrix is critical to its efficacy.
Numerous studies, including seven human clinical trials, demonstrate BioCell Collagen effectiveness, and bioavailability.
Numerous collagen supplements on the market lack human clinical research, contain insufficient amounts of active ingredients, or make fraudulent promises.
BioCell Collagen, on the other hand, is backed by clinical trials and a substantial body of research.
Numerous human clinical studies have demonstrated that 2 grams of BioCell Collagen daily is effective for joint health and 1 gram daily is effective for skin benefits.
These tests demonstrate conclusively that BioCell Collagen® is a novel, healthy aging dietary supplement ingredient that supports active joints and youthful-looking skin.
The findings of these investigations have been presented at scientific conferences and have been published in peer-reviewed journals.
Yes, millions of people have used BioCell Collagen safely and successfully since it was introduced to the market in 1998.
It was granted GRAS (Generally Recognized as Safe) status by an impartial expert safety panel following rigorous scientific examinations of not just safety and toxicity data, but also production practices in accordance with food Good Manufacturing Practices (GMP).
Numerous research studies, including seven human clinical trials, demonstrate BioCell Collagen effectiveness, and bioavailability.
BioCell Collagen is non-GMO, gluten-free, soy-free, shellfish-free, fish-free, egg-free, milk-free, peanut-free, and sugar-free.
1. Assists in regenerating the dermal matrix through the use of highly bioavailable building blocks
Collagen, hyaluronic acid (HA), and chondroitin sulfate are all necessary components of the skin dermis’s healthy structure and function.
As one ages, the concentrations of these components drop, resulting in the dermal matrix becoming disorganized or collapsing.
Clinical studies reveal that supplementing with BioCell Collagen improves the appearance of the skin from the inside out.
Collagen provides the tensile strength for the dermal matrix, which is composed of pulverized substances like as hyaluronic acid.
Additionally, boosting the density of dermal fibroblasts, which are responsible for the production of structural components of the dermal network, can help maintain the skin’s youthful appearance.
2. Increases skin moisture, turgidity, and hyaluronidase inhibition
Maintaining an adequate level of HA is crucial for maintaining a healthy skin structure and turgidity, as HA is responsible for water retention in the dermis of the skin.
With aging, HA and collagen levels decline, resulting in dermal dryness, skin sagging, and the production of wrinkles.
BioCell Collagen provides highly accessible HA to help mitigate the effects of natural degradation or photoaging.
During the 28-day testing period, human volunteers who received a daily dose of BioCell Collagen exhibited a 60-fold increase in HA levels in their blood.
The coordinated action of HA synthesis and hyaluronidases is required to maintain HA levels.
Hyaluronidase catalyzes the degradation of HA in response to a variety of physiological and pathological stimuli, including aging and inflammation.
It has been demonstrated that BioCell Collagen inhibits hyaluronidase.
Thus, BioCell Collagen can address a critical molecular actor involved in aging-associated dehydration while also replacing the skin dermis’s numerous vital structural components.
In 2011, BioCell Technology conducted a groundbreaking human skin study in which it was demonstrated that daily ingestion of BioCell Collagen for 12 weeks resulted in a significant reduction of facial lines and wrinkles, as well as increased hydration and stimulation of collagen biosynthesis, most likely from dermal fibroblasts.
Additionally, it resulted in an increase in hemoglobin levels in face skin tissue, indicating improved blood microcirculation in the dermis.
The majority of study participants reported improved skin texture, increased hydration, and less facial scaling.
The findings of the study were published in Clinical Interventions in Aging (2012).
The dosages of BioCell Collagen taken in our clinical trials were 1 g (1000 mg) per day for skin health and 2 g (2000 mg) per day for joint and skin health benefits.
No, not all collagen is identical or interchangeable.
Collagen type, source, molecular size, composition, and manufacturing technique all play a role in the indications and efficacy of various dietary supplement collagen products.
BioCell Technology, the manufacturer of BioCell Collagen, has spent nearly two decades conducting clinical trials and conducting research and development.
BioCell Technology invented hydrolyzed collagen type II, chondroitin sulfate, and hyaluronic acid matrix formulations and was given multiple patents for its technology.
Collagen is the most predominant protein in the body. A number of different types of collagen have been discovered among which type I/III and type II are the major types for the skin dermis and for the articular cartilage, respectively. Research showed that hydrolyzed collagen type II contained in BioCell Collagen stimulated the biosynthesis of collagen type II from the chondrocytes and that daily ingestion of BioCell Collagen increased the collagen content in the facial skin. This suggests that BioCell Collagen can increase all of the major types of collagen (I, II, and III) found in the joint, skin and other connective tissues.
Yes, millions of people have used BioCell Collagen safely and successfully since it was introduced to the market in 1998.
It was granted GRAS (Generally Recognized as Safe) status by an impartial expert safety panel following rigorous scientific examinations of not just safety and toxicity data, but also production practices in accordance with food Good Manufacturing Practices (GMP).
Numerous research studies, including seven human clinical trials, demonstrate BioCell Collagen effectiveness, and bioavailability.
BioCell Collagen is non-GMO, gluten-free, soy-free, shellfish-free, fish-free, egg-free, milk-free, peanut-free, and sugar-free.
BioCell Collagen is manufactured entirely in the United States of America and Germany.
Everyone can benefit from taking BioCell Collagen. Diet, age, stress, digestive system and physical activity (sports which impact joints), all affect our ability to provide the body with the nutritional raw materials it requires to properly support joint and connective tissue health. BioCell Collagen should be an essential nutritional component for those wanting to remain healthy and active throughout their life.
Yes. BioCell Collagen is affirmed GRAS (Generally Regarded As Safe) based upon the experts’ extensive review of diverse safety and toxicology studies using animal models as well as human subjects. Effective dose can be determined considering the weight of a pet.
No, glucosamine offers a partial approach to joint health. In contrast, BioCell Collagen is a multi-dimensional ingredient that supports both joint and skin health. BioCell Collagen is a clinically studied dietary ingredient composed of naturally-occurring hydrolyzed collagen type II peptides, chondroitin sulfate, hyaluronic acid. BioCell’s unique matrix is not a blend of individual ingredients. The synergy of biomolecules found in BioCell Collagen unique matrix offers multi-dimensional nutritional support for the health of connective tissues of the skin, joint, tendon, and ligament.
No, collagens are the most abundant proteins found in connective tissues of human and animal species.
No. There is no scientific evidence of incompatibility between collagen type 2 and 1&3 when taken together. The notion that if taken together, the two proteins will bind and form a complete protein and the body will not recognize it as collagen is misleading marketing rhetoric. Many collagen supplements on the market lack human clinical studies, do not contain efficacious ingredient quantities, or make false claims. .
In contrast, BioCell Collagen is backed by clinical studies and an extensive body of research. Multiple human clinical studies have been conducted on BioCell Collagen, demonstrating that 2 grams daily is effective for joint health, while 1 gram daily is effective for skin benefits. These studies provide solid evidence that BioCell Collagen is a unique, healthy aging dietary supplement ingredient that promotes active joints and younger-looking skin. The outcome of these studies was presented in scientific conferences and also published in scientific journals.
Liquid BioCell FAQ
Liquid BioCell uses a highly bioavailable liquid form of a patented sternal cartilage that is a matrix of collagen, hyaluronic acid and chondroitin. It is derived from a byproduct of humanely treated chickens raised free of GMOs, antibiotics and hormones on the world’s most reputable and regulated farms located in the US and Europe. As part of our commitment to sustainability, we use chicken byproduct from parts that the farms would otherwise discard after processing the chickens for their meat.
Hyaluronic acid is a natural compound that exists throughout the body and is most commonly found in the eyes, joints and skin. Its molecular structure gives it a unique ability to retain large amounts of water, which affects the body’s moisture content and directly impacts the appearance of wrinkles, fine lines, dry skin and skin’s firmness. It is also a crucial component of synovial fluid for sufficient joint lubrication.*
Naturally found in connective tissue, chondroitin sulfate is one of the building blocks of cartilage. Its job is to help cushion joints and provide elasticity and resistance. Chondroitin sulfate supports joint, bone, ligament and tendon health for optimal mobility and can play a key role in living a more active lifestyle as you age.*
In the simplest terms, Liquid BioCell consists of type II hydrolyzed collagen, a major component of healthy joints, youthful skin and connective tissue; hyaluronic acid (HA), essential to skin hydration, tissue maintenance and a youthful appearance; and chondroitin sulfate to support joint flexibility and lubrication.*
Liquid BioCell products were developed by collagen expert Asma Ishaq. Asma has pioneered the collagen industry and continues to lead as Chair of the Board of Directors for the Collagen Stewardship Alliance, dedicated to ingredient transparency, globally sustainable collagen sourcing, ingredient quality and integrity. As Modere CEO, Asma was recognized in 2021 by Forbes as a top CEO in the health and beauty ecommerce space. Liquid BioCell is a result of research that was being done on an ingredient called hyaluronic acid or HA, which was thought to be associated with longer life spans. The medical community and researchers were very interested in the science, however found that the natural state of HA was too large for the body to absorb. Asma and her team’s interest in this science led to the discovery of a unique natural source of HA, which also coexisted with collagen and chondroitin sulfate as it does in the human body. The raw material was tested and developed into micromolecules that could actually be absorbed by the body. This nutraceutical ingredient was awarded 7 US and international patents and is called BioCell Collagen.*
Results prove that the body readily recognizes and accepts Liquid BioCell in controlled clinical environments where researchers can compare collagen and hyaluronic acid levels in the skin and in the blood of participants at weekly intervals.
The data shows measured increases in collagen and hyaluronic acid among study participants, indicating Liquid BioCell is formulated at a molecular weight that is effectively absorbed into the bloodstream and isn’t broken down in the digestive system is the same way as typical collagen proteins.
Liquid BioCell features an advanced liquid delivery system that is designed not only to be easy to use, but also tastes good. And people are more likely to take a supplement consistently if it is easy to use, which in turn improves efficacy and results.
Patents help Modere protect our ingredients, processes and innovation. All 7 Collagen/HA Matrix patents have been awarded based on the technology’s unique composition. It’s the first formula ever to feature Bio-Optimized collagen, hyaluronic acid and chondroitin sulfate in a matrix that mimics human body composition. The formula’s usage and manufacturing process are also patented.
Dietary supplements are subject to strict FDA regulations in the United States. However, whereas drugs require FDA approval prior to sale, the FDA does not approve or reject dietary supplements, including those derived from a natural source like Liquid BioCell.
In Canada, Liquid BioCell and products containing this ingredient are authorized for sale by Health Canada, the country’s regulatory equivalent of the FDA (NPN: 80108933, 80090542, 80108932, 80096623, 80097727).
More information about studies on Liquid BioCell can be found on modere.com/collagensciences and on individual Liquid BioCell product pages, where you’ll find our Science of Collagen brochure. Additionally, a list of scientific references can be found at the end of this document. Every benefit claim we make is substantiated with scientific research. The FDA regulates supplement claims, and as a leader in collagen supernutraceuticals for over 20 years, Modere prioritizes FDA compliance. To avoid implied claims related to medical conditions or disease, we don’t publish specific studies in our printed materials.
Our independent research is conducted via multiple double-blind, randomized, placebo-controlled human clinical trials and is third-party validated. These criteria are universally considered the highest standard for clinical studies in the scientific community.
These are pictures of what Liquid BioCell has done for real people who took the daily dose for 12 weeks†.
Although selected studies on our ingredient have been published in peer-reviewed journals, Modere opts to strictly limit the publication of studies on Liquid BioCell in scientific journals in order to protect proprietary data. However, the physicians who sit on the Modere Scientific Advisory Board have had many years of experience using Liquid BioCell successfully with their patients.
Collagen is a buzzword right now, not only among social media influencers and beauty bloggers, but in the medical community as well. Unfortunately, many so-called “experts” are inadvertently spreading misinformation about collagen supplementation. While it is true that many collagen products are more hype than help, popular media figures and even physicians who make generalizations about unproven or false claims by manufacturers are often not educated on the latest research.
Attempts to discredit collagen supplements do not take into account our clinical studies, which prove that the unique Collagen/HA Matrix in Liquid BioCell works very differently than typical hydrolyzed collagen. When shopping for a collagen supplement, look for one that is backed by clinical research. Make sure that research cited includes direct references to the specific ingredient or product you’re considering.
Liquid BioCell is not a drug; it is a nutritional supplement. There is no evidence that Liquid BioCell interferes with any medications. However, if you’re on medication, we recommend that you speak with your physician before starting any new supplement.
No studies have been done on Liquid BioCell during pregnancy. We encourage you to speak with your physician before starting a new supplement, whether or not you are pregnant.
